HMG 150 IU
Dragon Pharma

HMG 150 IU

Product Information Compound Details
Dragon Pharma
Active Substance Human Menopausal Gonadotropin (HMG) Menotropins (FSH & LH Activity)
150 IU/vial
Strength 150 IU/vial
Package 1 × 2 mL Vial
Form Lyophilized Powder
Drug Class Gonadotropin
Hormone Type Glycoprotein Hormone
Manufacturer Dragon Pharma
Shipping :
International
U.S. Domestic
Out of stock
Product Overview

HMG 150 IU by Dragon Pharma

HMG 150 IU is a lyophilized powder injectable manufactured by Dragon Pharma, containing Human Menopausal Gonadotropin (HMG) at a strength of 150 IU per vial.

Human Menopausal Gonadotropin Injectable

Human menopausal gonadotropin (HMG), also known as menotropins, is a purified urinary extract containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity in roughly equivalent amounts. It is FDA-approved for fertility treatment in both men and women under brand names such as Menopur and Repronex, and is available by prescription only.

In clinical practice, HMG is used for controlled ovarian hyperstimulation in women undergoing assisted reproductive technologies, and for stimulation of spermatogenesis in men with hypogonadotropic hypogonadism when HCG alone has failed to restore adequate sperm production. The FSH component stimulates Sertoli cells in the testes, which is essential for spermatogenesis, while the LH component stimulates Leydig cells to produce testosterone.

In non-medical bodybuilding contexts, HMG is sometimes referenced as a component of post-cycle therapy protocols, typically alongside HCG, to provide FSH stimulation in addition to LH-like activity. However, community PCT protocols are typically much shorter (1–2 weeks) than clinical fertility protocols (3–12 months), and may be insufficient for meaningful spermatogenic recovery.

Key Benefits of HMG 150 IU

  • Contains both FSH and LH activity for dual gonadotropin support
  • FSH component supports spermatogenesis through Sertoli cell stimulation
  • LH component supports testosterone production through Leydig cell stimulation
  • Commonly referenced alongside HCG in recovery protocols
  • Lyophilized powder form for reconstitution flexibility
Form

Lyophilized Powder

HMG 150 IU is supplied as a lyophilized (freeze-dried) powder in a 2 mL vial. This form requires reconstitution with a suitable diluent before use.

Product Profile

Human Menopausal Gonadotropin Profile

Human menopausal gonadotropin is a urinary-derived gonadotropin preparation containing roughly equivalent amounts of FSH and LH bioactivity, providing dual stimulation of both gametogenesis and steroidogenesis.

Gonadotropin Hormone (FSH & LH Activity)

HMG's FSH component binds to FSH receptors on Sertoli cells in males and granulosa cells in females, driving gametogenesis through cAMP/PKA signaling and gene expression essential for sperm and egg development. The LH component acts on Leydig cells in males (stimulating testosterone production) and theca cells in females (stimulating androgen precursor production).

The combination of both activities in HMG provides more complete gonadal stimulation than either gonadotropin alone. FSH drives the cellular proliferation and maturation processes required for spermatogenesis, while LH provides the steroidogenic signals needed for testosterone production. This dual activity is why HMG is typically added in clinical settings when HCG monotherapy has failed to restore adequate sperm production.

A 2023 randomized study in males with hypogonadotropic hypogonadism found that combination therapy with HCG and HMG produced higher mean maximum testosterone levels (710.4 ng/dL) compared to HCG alone, and the combination group showed the highest increment in testicular volume.

Release Profile

Dual FSH and LH Activity

HMG's FSH component has a half-life of approximately 30 hours, while the LH component clears in approximately 24 hours. Once-daily dosing is sufficient for steady-state levels, which are reached after approximately 3–5 days of consecutive injections.

HMG 150 IU vs Other Dragon Pharma Preparations

Dragon Pharma offers several hormonal products that are commonly referenced in recovery and fertility contexts. HCG 5000 IU provides LH-like activity alone, stimulating testosterone production but lacking the FSH component needed for spermatogenesis. Clomid and Nolvadex are selective estrogen receptor modulators that work indirectly by increasing endogenous gonadotropin release through the hypothalamic-pituitary axis. Caber is a dopamine agonist referenced for prolactin management. For protocols requiring FSH activity, HMG is unique among these options in providing direct FSH receptor stimulation.

Dosage & Usage

HMG 150 IU Dosage & Usage

The information below is provided for educational reference only. HMG is a prescription medication approved for fertility treatment; medical use requires appropriate diagnosis, clinical supervision and ongoing monitoring. Non-medical use falls outside approved indications.

Typical Dosage Ranges

In medically supervised fertility treatment, HMG dosing is individualized based on the indication, patient response and clinical monitoring. For male infertility, clinical protocols typically use 75–150 IU every other day alongside ongoing HCG therapy, often continued for 3–12 months. In non-medical bodybuilding contexts, HMG is commonly referenced at 75 IU every other day for 1–2 weeks as part of post-cycle recovery protocols.

Use Case Common Reference Range Injection Frequency
Clinical fertility (male, with HCG) 75–150 IU Every other day, 3–12 months
Clinical fertility (female, ART) 150–225 IU initial, titrated Daily, per physician monitoring
Non-medical recovery reference 75 IU Every other day, 1–2 weeks
Enhanced recovery protocol 75–150 IU Every other day alongside HCG

Stacking & Cycle Considerations

In clinical and community settings, HMG is most commonly referenced alongside HCG 5000 IU. The combination provides LH stimulation (HCG and HMG's LH component) for testosterone production plus FSH stimulation (HMG) for spermatogenesis. Clinical protocols typically add HMG when HCG monotherapy has not restored adequate sperm production after 6–12 months.

Some protocols also reference selective estrogen receptor modulators such as Clomid or Nolvadex alongside HMG to support endogenous gonadotropin release through a different mechanism. Community PCT protocols are typically much shorter than clinical fertility protocols, which may limit their effectiveness for spermatogenic recovery.

Managing Side Effects

HMG can cause injection-site reactions including pain, redness, and swelling. Headache, abdominal discomfort, and nausea have been reported in clinical use. In women undergoing ovarian stimulation, HMG carries a risk of ovarian hyperstimulation syndrome (OHSS), which requires careful monitoring.

Because HMG is a urinary-derived product, the risk of transmission of a pathogen (known or unknown) cannot be completely excluded. Local allergic reactions due to protein contamination have also been reported.

Post-Cycle Therapy (PCT)

HMG is sometimes referenced as a component of post-cycle therapy in non-medical bodybuilding contexts, typically after initial HCG administration has restored testicular volume and testosterone production. The rationale is that HMG's FSH component provides additional support for spermatogenesis that HCG alone cannot provide.

Community PCT protocols for HMG are typically short (1–2 weeks), while clinical fertility protocols continue for 3–12 months. The shorter timeframe may be insufficient for meaningful spermatogenic recovery, as spermatogenesis requires approximately 72–90 days per cycle.

Important

Individual Response Varies

Dosing strategies and recovery protocols should be adjusted based on individual factors and bloodwork where possible. The information above is for educational reference and does not constitute medical advice.

Safety & Information

Human Menopausal Gonadotropin Safety Information

HMG is a prescription medication approved for fertility treatment. Non-medical use falls outside approved indications and should be considered in the context of potential risks.

Important Safety Information

HMG is a potent gonadotropin capable of causing mild to severe adverse reactions and should only be used under medical supervision by physicians experienced in infertility management. The product is contraindicated in women with tumors of the pituitary or hypothalamus, ovarian or uterine carcinoma, pregnancy, gynaecological haemorrhage of unknown cause, or hypersensitivity to the active substance.

The active ingredient in HMG is extracted from human urine, and the risk of transmission of a pathogen (known or unknown) cannot be completely excluded.

Important

Non-Medical Use

HMG is not approved for bodybuilding, performance enhancement, or post-cycle recovery. Any such use falls outside approved indications. Product potency and laboratory verification do not establish that non-medical use is safe or appropriate for an individual.

Potential Adverse Effects

Commonly reported adverse reactions include headache, abdominal discomfort, nausea, and injection-site pain or swelling. Less frequent effects include fatigue, breast tenderness, hot flushes, mood changes, and drowsiness.

In women undergoing ovarian stimulation, HMG carries a risk of ovarian hyperstimulation syndrome (OHSS), a potentially serious condition characterized by marked ovarian enlargement, high serum sex steroids, and increased vascular permeability. Severe OHSS can include thromboembolic events and requires immediate medical attention.

Multiple pregnancies are also a risk in female fertility treatment, with a Japanese survey reporting twin or higher-order pregnancies in 20.48% of cases.

Conditions Requiring Medical Evaluation

Before starting HMG treatment, patients should be evaluated for hypothyroidism, adrenocortical deficiency, hyperprolactinemia, and pituitary or hypothalamic tumors. Women should be evaluated for ovarian cysts or enlargement not due to polycystic ovarian syndrome, and for conditions that would make pregnancy inappropriate.

Patients with active thromboembolic disease should not receive HMG, and those at risk of blood clots should inform their physician as gonadotropins may increase this risk.

Monitoring During Use

In medically supervised HMG therapy, monitoring typically includes ultrasound examinations and serum estradiol measurements to assess ovarian response and minimize the risk of OHSS. For male fertility protocols, sperm analysis is used to assess treatment response.

Laboratory testing of the product itself would be separate from any clinical monitoring of the individual. No published laboratory reports are currently available for this specific Dragon Pharma product.

Product Care

Storage & Handling

Lyophilized HMG should be stored in its original container, protected from light. Before mixing, MENOPUR powder can be stored in the refrigerator or at room temperature between 37°F to 77°F (3°C to 25°C). The product should be used right after mixing, and unused reconstituted solution should be discarded.

Keep all medications and injectable products out of the reach of children. Follow the storage instructions provided with the product packaging.

Shipping & Authenticity

Shipping & Product Authenticity

HMG 150 IU by Dragon Pharma is supplied through the official distribution chain and shipped in original manufacturer packaging with discreet, privacy-focused handling.

USA Domestic 3–5 business days
International 10–15 business days
Order Processing 24–48 business hours
Tracking Provided after dispatch
Direct Supply

Discreet Delivery & Original Packaging

The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details. Products are supplied through the official Dragon Pharma distribution chain.

What to Expect

  • Orders are processed after payment confirmation
  • USA Domestic shipping is typically faster when local stock is selected
  • International orders include tracking, though update frequency may vary by destination
  • Multiple warehouses may result in separate shipments when applicable

Authenticity Verification

To verify your HMG 150 IU product, use the security code on the vial label and cross-check it on the Dragon Pharma official site. Official presentation, batch-linked lab proof when available, and original packaging help reinforce product legitimacy and buyer confidence.

For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.

Storage

HMG 150 IU Storage

Proper storage conditions help preserve peptide hormone stability and overall product integrity throughout shelf life.

Recommended Conditions

Store the lyophilized powder in its original container, protected from light. Before mixing, the powder can be stored in the refrigerator or at room temperature between 37°F to 77°F (3°C to 25°C). The product should be used right after mixing, and unused reconstituted solution should be discarded.

Protect from excessive heat and direct light. Keep out of reach of children.

Quick Reference

Do & Don't

  • Do store lyophilized powder protected from light
  • Do store at 3–25°C before mixing
  • Do use immediately after reconstitution
  • Don't freeze reconstituted solution
  • Don't expose to excessive heat
  • Don't use if solution looks cloudy or contains particles
Frequently Asked Questions

HMG 150 IU FAQ

Answers to common questions about HMG 150 IU, Human Menopausal Gonadotropin, its clinical applications, and product information.

What is HMG 150 IU used for?

HMG 150 IU contains human menopausal gonadotropin, which is FDA-approved for fertility treatment in both men and women. In men, it is used to stimulate spermatogenesis in hypogonadotropic hypogonadism when HCG alone has failed to restore adequate sperm production. In non-medical bodybuilding contexts, HMG is sometimes referenced in post-cycle recovery protocols, though such use falls outside approved indications.

How often should HMG 150 IU be injected?

Clinical fertility protocols for male infertility typically use 75–150 IU every other day alongside ongoing HCG therapy. For female fertility treatment, dosing is individualized by a physician based on ovarian response monitoring. Community recovery protocols commonly reference 75 IU every other day for 1–2 weeks.

Does HMG 150 IU require PCT?

HMG is itself sometimes used as a component of post-cycle therapy rather than requiring PCT afterward. In non-medical contexts, HMG is typically used alongside HCG 5000 IU to provide FSH stimulation in addition to LH-like activity. Some protocols also include selective estrogen receptor modulators such as Clomid or Nolvadex.

What does Human Menopausal Gonadotropin do?

HMG contains both FSH and LH activity. The FSH component stimulates Sertoli cells in the testes, supporting spermatogenesis, while the LH component stimulates Leydig cells to produce testosterone. This dual activity makes HMG uniquely valuable for fertility applications where both sperm production and testosterone support are needed.

How long does HMG take to work?

HMG's FSH component has a half-life of approximately 30 hours, and steady-state levels are reached after approximately 3–5 days of consecutive injections. However, meaningful spermatogenic recovery requires 72–90 days per cycle, so clinical fertility protocols typically continue for 3–12 months.

Is HMG the best recovery compound?

There is no single compound that is universally best for recovery. HMG provides both FSH and LH activity, while HCG 5000 IU provides primarily LH-like activity. Clinical studies show that combination therapy with HCG and HMG produces higher maximum testosterone levels than HCG alone. The appropriate approach depends on individual circumstances and goals.

What is the difference between HMG and HCG?

HMG contains both FSH and LH activity, while HCG primarily mimics LH activity only. The FSH component in HMG provides stimulation of Sertoli cells for spermatogenesis, which HCG cannot do. This is why clinical protocols add HMG when HCG alone has failed to restore adequate sperm production.

What is the difference between HMG and Clomid?

HMG directly provides FSH and LH activity at the gonadal level, while Clomid works indirectly by blocking estrogen feedback at the hypothalamus and pituitary, increasing endogenous gonadotropin release. HMG's effects do not depend on a functioning hypothalamic-pituitary axis, while Clomid's do.

Is 150 IU a lot of HMG?

150 IU is a standard clinical dose used in female fertility treatment, typically as a starting dose before titration based on ovarian response. For male fertility protocols, 75–150 IU every other day is commonly referenced. Doses are individualized based on indication and clinical response.

What strength is HMG 150 IU?

HMG 150 IU is labeled at 150 IU of human menopausal gonadotropin per vial. It is supplied as a lyophilized powder in a 2 mL vial, requiring reconstitution before use.

Is HMG 150 IU lab tested?

No published laboratory report is currently available for this specific product. Product potency and purity verification would apply to tested samples only and should not be interpreted as a measurement of every vial or production batch.

How should HMG 150 IU be reconstituted?

Lyophilized HMG is typically reconstituted with the diluent provided or a suitable solvent such as Bacteriostatic Water. The product should be used right after mixing, and unused reconstituted solution should be discarded. Proper sterile technique should be used during reconstitution.

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