Axiolabs
Axiolabs
Mastaplex 100 mg
Product Information
Compound Details
Active Substance
Drostanolone Propionate
Short-Acting DHT-Derived Anabolic-Androgenic Steroid
100 mg/mL
Strength
100 mg/mL
Package
10 mL Vial
1,000 mg Total Labeled Content
Form
Oil-Based Injectable
MCT Oil
Drug Class
Anabolic-Androgenic Steroid
Estimated Half-Life
Approximately 2–3 Days
Manufacturer
Axiolabs
$114.00
Shipping :
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U.S. Domestic
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- Overview
- Profile
- Usage
- Safety
- Shipping
- Storage
- FAQ
- Reviews
Product Overview
Mastaplex 100 mg by Axiolabs
Mastaplex 100 mg is an oil-based drostanolone propionate injectable manufactured by Axiolabs and dosed at 100 mg/mL in a 10 mL vial.
Drostanolone Propionate Injectable
Mastaplex 100 mg is an injectable anabolic-androgenic steroid containing drostanolone propionate, a synthetic DHT-derived anabolic agent. Drostanolone, also known as dromostanolone, is a modified form of dihydrotestosterone featuring a methyl group at the carbon-2 alpha position, which considerably increases its anabolic strength by heightening its resistance to metabolism by the 3-hydroxysteroid dehydrogenase enzyme in skeletal muscle tissue . Its propionate ester provides a relatively short duration of action, with a half-life of approximately two to three days following intramuscular injection.
In clinical medicine, drostanolone propionate was first approved in the United States in 1961 for the treatment of female breast cancer, marketed under the brand names Masteron and Drolban. It was also used to lower plasma cholesterol. However, it is no longer manufactured or sold by pharmaceutical companies for clinical use, having been phased out as more effective breast cancer treatments became available. In non-medical bodybuilding contexts, drostanolone propionate is extensively referenced during cutting phases and contest preparation for its reputation for producing hard, dry muscle appearance, enhanced vascularity, and minimal water retention. Such use falls outside approved indications.
Drostanolone exerts its effects by binding to androgen receptors, competing with androgen binding sites but not with estrogen receptors. Its inability to be converted into estrogenic metabolites distinguishes it from aromatizable compounds, contributing to its "dry" profile. Research has shown that drostanolone can compete with dihydrotestosterone for binding to specific receptor proteins in target tissues. Non-medical use at supraphysiologic doses carries risks including virilization in women, prostatic hypertrophy and impotence in men, acne, abnormal lipids, and hepatotoxicity.
Key Benefits of Mastaplex 100 mg
- Short-acting propionate ester for flexible dosing
- DHT-derived compound with no estrogen conversion
- Commonly referenced for muscle hardening and vascularity
- MCT oil carrier for smooth, consistent formulation
- 100 mg/mL concentration for precise dosing accuracy
Carrier Oil
MCT Oil Formulation
Mastaplex 100 mg uses MCT oil as its carrier oil, providing the oil base for the drostanolone propionate formulation.
Product Profile
Drostanolone Propionate Profile
Drostanolone propionate is a short-acting DHT-derived injectable anabolic steroid with a distinctive profile, characterized by its lack of estrogen conversion and reputation for producing a hard, dry physique aesthetic.
Short-Acting DHT-Derived Injectable Anabolic
Drostanolone propionate is the propionate ester of drostanolone (2α-methyl-17β-hydroxy-5α-androstan-3-one), a synthetic anabolic steroid derived from dihydrotestosterone. The methyl group at carbon-2 alpha significantly enhances the anabolic strength of the compound by increasing its resistance to metabolism by 3-hydroxysteroid dehydrogenase in skeletal muscle tissue . The propionate ester attached to the 17-beta hydroxyl group increases lipophilicity and slows absorption from the injection site, prolonging the therapeutic window compared to unesterified drostanolone.
The half-life of drostanolone propionate is approximately two to three days following intramuscular injection, which requires more frequent administration than longer-acting esters such as drostanolone enanthate. Once in the bloodstream, the ester is cleaved to yield free (active) drostanolone. Research has demonstrated that drostanolone competes with androgen binding sites but does not interact with estrogen receptors, indicating that its effects are mediated through androgen receptor binding rather than estrogen receptor interaction.
Drostanolone propionate is approximately five times as potent as natural methyltestosterone. In bodybuilding contexts, it is valued for its ability to produce a hard, dry look, particularly at low body fat levels where its cosmetic effects become most visible. The compound does not aromatize, meaning it does not convert to estrogen, which contributes to its reputation for minimal water retention.
Defining Characteristic
Short Half-Life and No Aromatization
Drostanolone propionate's short half-life of 2–3 days supports frequent administration for stable blood levels, while its inability to aromatize distinguishes it from testosterone-based compounds and contributes to its "dry" profile.
Mastaplex 100 mg vs Other Axiolabs Preparations
Axiolabs produces several injectable anabolic products referenced in different contexts. Mastaplex 100 mg is a drostanolone propionate product, placing it among the shorter-acting injectable options alongside Testaplex P 100 (testosterone propionate).
For a longer-acting drostanolone ester, Mastaplex 200 (drostanolone enanthate) offers less frequent administration. For bodybuilders considering other DHT-derived compounds, Primoplex (methenolone) is commonly referenced for similar cutting applications with a milder profile. The choice between these compounds depends on individual goals, injection frequency preference, and tolerance for androgenic side effects.
Dosage & Usage
Mastaplex 100 mg Dosage & Usage
The information below is provided for educational reference only. Drostanolone propionate is a prescription medication; medical use requires appropriate diagnosis and clinical supervision. Non-medical use falls outside approved indications.
Typical Dosage Ranges
In non-medical bodybuilding contexts, drostanolone propionate is commonly referenced in the range of 300–400 mg per week, typically administered every other day due to its short half-life. Some users reference doses as low as 200 mg per week for milder effects, while more experienced users may reference 500–600 mg per week. A professional bodybuilder has publicly referenced using 300 mg weekly during contest preparation.
| Use Case | Common Reference Range | Injection Frequency |
|---|---|---|
| Bodybuilding (non-medical, moderate) | 200–300 mg / week | Every other day |
| Bodybuilding (non-medical, standard) | 300–400 mg / week | Every other day |
| Advanced (non-medical) | 500–600 mg / week | Every other day or daily |
Stacking & Cycle Considerations
In non-medical bodybuilding contexts, drostanolone propionate is frequently referenced as a stacking compound during cutting cycles, often combined with a testosterone base. It is commonly stacked with Testaplex P 100 (testosterone propionate) for synergistic effects, as both are short-acting esters. Some users report that drostanolone propionate can help manage estrogen-related side effects from testosterone without the need for aromatase inhibitors. It is also sometimes combined with oral compounds such as Stanoplex (stanozolol) during the final weeks of contest preparation.
Managing Side Effects
Drostanolone propionate is a DHT-derived compound and can accelerate hair loss in individuals predisposed to male pattern baldness. Acne flare-ups are also commonly reported, particularly in those prone to acne. Lipid profile monitoring is relevant as DHT-derived compounds can negatively affect HDL cholesterol.
Hepatotoxicity has been documented with drostanolone propionate use. A case report described a 19-year-old male who developed severe canalicular cholestasis after using drostanolone propionate at 200 mg every 96 hours for 56 days alongside other anabolic steroids. Women should be aware of virilization risk including voice deepening and clitoral enlargement.
Post-Cycle Therapy (PCT)
Drostanolone propionate suppresses endogenous testosterone production, and post-cycle therapy is commonly recommended after a cycle. Agents such as Clomiplex and Tamoxiplex are frequently referenced for this purpose. Due to the short propionate ester, PCT can typically begin sooner after the final injection compared to longer-acting compounds.
Important
Individual Response Varies
Dosing strategies and support protocols should account for individual experience and health status. The information above is for educational reference and does not constitute medical advice.
Safety & Information
Drostanolone Propionate Safety Information
Drostanolone propionate is an anabolic steroid with significant androgenic and hepatic considerations. Medical use requires appropriate diagnosis and ongoing clinical supervision.
Important Safety Information
Drostanolone propionate has been associated with hepatotoxicity, including cholestatic hepatitis. A documented case reported severe canalicular cholestasis with a bilirubin level of 41.9 mg/dl and GPT of 114 IU/l in a young male using drostanolone propionate alongside other anabolic steroids. Biochemical tests of liver function may show abnormalities sometimes severe enough to cause jaundice.
As a DHT-derived compound, drostanolone propionate can accelerate androgenic effects including male pattern baldness in predisposed individuals and acne. It may also negatively affect lipid profiles, particularly HDL cholesterol.
Important
Non-Medical Use
Drostanolone propionate is not approved for bodybuilding or athletic performance enhancement. Non-medical use falls outside approved indications and may carry additional health risks beyond those associated with supervised medical use.
Potential Adverse Effects
Documented adverse effects of drostanolone include virilization in women, prostatic hypertrophy, impotence and azoospermia in men, acne, and abnormal lipids. Hepatotoxicity is a significant concern, with cholestatic hepatitis reported.
As a DHT-derived compound, drostanolone propionate can accelerate hair loss in individuals with a genetic predisposition. Acne flare-ups are commonly reported. Drostanolone suppresses endogenous testosterone production, which can affect libido and fertility.
Conditions Requiring Medical Evaluation
Drostanolone propionate is not appropriate for individuals with pre-existing hepatic disease, cardiovascular conditions, or lipid disorders. Medical evaluation is required before any consideration of use. The compound is contraindicated in pregnancy and should not be used by women who are pregnant or breastfeeding. Women considering use should be aware of virilization risk, which may be irreversible.
Monitoring During Therapy
In non-medical contexts, blood work to monitor liver enzymes and lipid profiles is frequently recommended during and after cycles. These monitoring practices are not a substitute for clinical oversight, which is required for safe use of any anabolic steroid. No specific monitoring protocol has been established for non-medical use.
Product Care
Storage & Handling
Store in a cool, dry place at controlled room temperature. Protect from excessive heat, moisture, and direct light. Keep the vial in its original packaging until use. Do not freeze. Before administration, inspect the solution and avoid use if it appears cloudy, discolored, contains particulate matter, or if the vial or seal is compromised. Keep out of reach of children.
Further Safety Information
Shipping & Authenticity
Shipping & Product Authenticity
Mastaplex 100 mg is shipped in original manufacturer packaging with discreet, privacy-focused handling.
USA Domestic 3–5 business days
International 10–15 business days
Order Processing 24–48 business hours
Tracking Provided after dispatch
Direct Supply
Discreet Delivery & Original Packaging
Outer packaging remains discreet with no external product details. Products are supplied in original manufacturer presentation.
What to Expect
- Orders are processed after payment confirmation
- USA Domestic shipping is typically faster when local stock is selected
- International orders include tracking, though update frequency may vary
- Multiple warehouses may result in separate shipments when applicable
Authenticity Verification
To verify product authenticity, examine the packaging for manufacturer security features and compare against official Axiolabs presentation. Original packaging and consistent labeling help confirm product legitimacy.
For complete delivery details, please see our Shipping Info page.
Storage
Mastaplex 100 mg Storage
Proper storage conditions help preserve formulation stability and overall product integrity throughout shelf life.
Recommended Conditions
Store at controlled room temperature (15–25°C) and protect from excessive heat, moisture, and direct light. Keep the vial in its original packaging until use. Do not freeze. Before administration, inspect the solution and avoid use if it appears cloudy, discolored, contains particulate matter, or if the vial or seal is compromised. Keep out of reach of children.
Quick Reference
Do & Don't
- Do store at 15–25°C
- Do keep in original packaging
- Do inspect before each use
- Don't freeze the vial
- Don't expose to direct sunlight
- Don't use if solution looks abnormal
Frequently Asked Questions
Mastaplex 100 mg FAQ
Answers to common questions about Mastaplex 100 mg, drostanolone propionate, dosing, and product characteristics.
What is Mastaplex 100 mg used for?
Mastaplex 100 mg contains drostanolone propionate, an injectable anabolic steroid. Historically, it was approved for treating female breast cancer and lowering cholesterol, but it is no longer manufactured for clinical use. In non-medical bodybuilding contexts, it is commonly referenced during cutting phases for muscle hardening and vascularity, though such use falls outside approved indications.
How often should Mastaplex 100 mg be injected?
Drostanolone propionate has a half-life of approximately two to three days following intramuscular injection. In non-medical contexts, it is typically referenced as being administered every other day to maintain stable blood levels. This is distinct from medically supervised dosing, which is individualized by a clinician.
Does Mastaplex 100 mg require PCT?
Yes. Drostanolone propionate suppresses endogenous testosterone production, and post-cycle therapy is commonly recommended after a cycle. Agents such as Clomiplex or Tamoxiplex are commonly referenced for this purpose. Due to the short propionate ester, PCT can typically begin sooner after the final injection compared to longer-acting compounds.
What does drostanolone propionate do?
Drostanolone propionate binds to androgen receptors, competing with androgen binding sites but not with estrogen receptors. It is a modified form of dihydrotestosterone with a methyl group at carbon-2 alpha that increases its anabolic strength. It does not aromatize to estrogen, contributing to its reputation for producing a hard, dry physique appearance.
How long does drostanolone propionate take to work?
In bodybuilding discussions, users sometimes report noticeable hardening and vascularity effects within the first 1–2 weeks of use at 300–400 mg per week. The cosmetic effects are most visible at low body fat levels, where muscle definition and vascularity become more apparent. Individual response varies considerably.
Is drostanolone propionate the best injectable for cutting?
There is no universally "best" injectable for cutting. Drostanolone propionate is commonly referenced for its hardening effects, but Primoplex (methenolone) and Testaplex P 100 (testosterone propionate) are also widely discussed. The appropriate choice depends on individual goals, body fat levels, and tolerance for androgenic side effects.
What is the difference between drostanolone propionate and drostanolone enanthate?
Both are drostanolone esters, but they differ in release rate. Drostanolone propionate has a short half-life of approximately 2–3 days, requiring every-other-day injections. Drostanolone enanthate has a longer ester and is typically referenced for less frequent administration. Axiolabs offers Mastaplex 200 as its drostanolone enanthate product.
What is the difference between drostanolone propionate and Primobolan?
Both are DHT-derived compounds used in cutting phases, but they have different profiles. Drostanolone is generally considered more aggressive for producing a hard, dry look, while Primobolan (methenolone) is often described as milder and more sustainable. Axiolabs offers Primoplex as its methenolone product.
Is 400 mg of drostanolone propionate a lot?
In non-medical bodybuilding contexts, 400 mg per week is within the commonly referenced range of 300–400 mg per week. Mastaplex 100 mg contains 100 mg/mL, so 400 mg would equal 4 mL per week. Dosage appropriateness depends on individual factors and the overall cycle context.
What strength is Mastaplex 100 mg?
Mastaplex 100 mg is labeled at 100 mg of drostanolone propionate per mL. It is supplied in a 10 mL vial, giving 1,000 mg of total labeled drostanolone propionate content per vial.
Is Mastaplex 100 mg lab tested?
Lab testing information for Mastaplex 100 mg is not available on this page. For product-specific testing inquiries, please contact customer support.
Can drostanolone propionate cause hair loss?
Yes. As a DHT-derived compound, drostanolone propionate can accelerate hair loss in individuals with a genetic predisposition to male pattern baldness. If you are already experiencing hair thinning, drostanolone may accelerate the process. This is a significant consideration for users concerned about hair retention.
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Drug Class
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Estimated Half-Life
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