Primoplex 100 mg is an oil-based methenolone enanthate injectable manufactured by Axiolabs and dosed at 100 mg/mL in a 10 mL vial.
Primoplex 100 mg is an injectable anabolic-androgenic steroid containing methenolone enanthate, a long-acting DHT-derived anabolic agent. Methenolone, also known as primobolan, was first described in 1960 and introduced as an injectable drug in 1962. It is a modification of dihydrotestosterone (DHT) with weak androgenic activity and a moderate anabolic effect, notable for its ability to bind firmly to androgen receptors, stronger than testosterone. The enanthate ester provides an extended release profile, with a biological half-life of approximately 10.5 days following intramuscular injection.
In clinical medicine, methenolone enanthate has been indicated for diseases and states requiring an increase in protein production to improve the patient's general condition or to prevent damage resulting from catabolic processes, such as consumptive diseases, cachexia, and advanced carcinoma of the breast or genital organs in women. It was originally prescribed for muscle loss after operations, infections, long-term illnesses, aggressive therapy with corticoids or malnutrition, and in some cases for osteoporosis and breast cancer, and was commonly used to promote weight gain in infants without any side effects. In non-medical bodybuilding contexts, methenolone enanthate is commonly referenced as one of the mildest anabolic steroids, valued for lean muscle preservation during cutting phases and its minimal estrogenic side effects. Such use falls outside approved indications.
Methenolone exerts its effects by binding to androgen receptors in muscle tissue, increasing nitrogen retention and protein synthesis without converting to estrogen. As a DHT derivative, it is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites, which distinguishes it from testosterone-based compounds and contributes to its "dry" profile. Non-medical use at supraphysiologic doses carries risks including suppression of endogenous testosterone production, lipid profile disruption, and androgenic effects such as acne and hair loss in predisposed individuals.
Primoplex 100 mg uses MCT oil as its carrier oil, providing the oil base for the methenolone enanthate formulation.
Methenolone enanthate is a long-acting DHT-derived injectable anabolic steroid with a distinctive profile, characterized by its extended release, lack of estrogen conversion, and reputation for being one of the mildest anabolic agents available.
Methenolone enanthate is the enanthate ester of methenolone (17β-hydroxy-1-methyl-5α-androst-1-en-3-one), a synthetic anabolic steroid derived from dihydrotestosterone (DHT). The 1-methyl group provides oral bioavailability, but the injectable enanthate form bypasses hepatic breakdown on first pass, resulting in higher survival rates and better bioavailability compared to the oral acetate version. The enanthate ester attached to the 17-beta hydroxyl group increases lipophilicity and slows absorption from the injection site, extending the therapeutic window.
The pharmacokinetic profile of methenolone enanthate includes a biological half-life of approximately 10.5 days following intramuscular injection. This long half-life supports less frequent administration, typically once or twice weekly, compared to the shorter-acting acetate ester. Once in the bloodstream, the ester is cleaved by esterases to yield free (active) methenolone. Methenolone binds firmly to androgen receptors, stronger than testosterone, which contributes to its anabolic effects.
Methenolone enanthate is considered one of the mildest anabolic steroids due to its low androgenic activity and lack of estrogenic side effects. It does not convert to estrogen and has lower estrogenic properties than nandrolone, which makes it a suitable choice for individuals very susceptible to estrogenic side effects. Its anabolic activity is slightly lower than that of nandrolone, quite likely because it is non-estrogenic.
Methenolone enanthate's half-life of approximately 10.5 days supports infrequent administration, while its inability to aromatize distinguishes it from testosterone-based compounds and contributes to its reputation as a "clean" anabolic agent.
Axiolabs produces several injectable anabolic products referenced in different contexts. Primoplex 100 mg is a methenolone enanthate product, placing it among the longer-acting injectable options alongside Testaplex E 250 (testosterone enanthate) and Decaplex 250 (nandrolone decanoate).
For bodybuilders considering other DHT-derived compounds for cutting, Mastaplex 100 (drostanolone propionate) is commonly referenced for similar applications with a more aggressive hardening effect. For those preferring oral options, Oxandroplex (oxandrolone) is often discussed as another mild compound for cutting phases. The choice between these compounds depends on individual goals, injection frequency preference, and tolerance for androgenic side effects.
The information below is provided for educational reference only. Methenolone enanthate is a prescription medication in many jurisdictions; medical use requires appropriate diagnosis and clinical supervision. Non-medical use falls outside approved indications.
In non-medical bodybuilding contexts, methenolone enanthate is commonly referenced in the range of 400–800 mg per week for men, with beginners typically starting at 200–400 mg per week and intermediate to advanced users referencing 400–600 mg per week. Women are generally referenced at 50–100 mg per week due to its low androgenic properties. Due to the long enanthate ester, doses are typically administered once or twice weekly to maintain stable blood levels.
| Use Case | Common Reference Range | Injection Frequency |
|---|---|---|
| Bodybuilding (non-medical, beginner) | 200–400 mg / week | Once or twice weekly |
| Bodybuilding (non-medical, intermediate/advanced) | 400–600 mg / week | Twice weekly |
| Women (non-medical) | 50–100 mg / week | Once weekly |
| Advanced (non-medical, higher end) | 600–800 mg / week | Twice weekly |
In non-medical bodybuilding contexts, methenolone enanthate is frequently referenced as a base compound or stacking partner during cutting cycles, often combined with a testosterone base. It is commonly stacked with Testaplex P 100 (testosterone propionate) or Testaplex E 250 (testosterone enanthate) for synergistic effects. Some users report that methenolone can partially reduce the need for aromatase inhibitors on moderate testosterone doses, but it is not a complete replacement at higher testosterone doses. It is also sometimes combined with oral compounds such as Stanoplex (stanozolol) during the final weeks of contest preparation.
Cycle structure, duration, and support compounds should be considered in the context of individual experience, health status, and bloodwork where possible.
Methenolone enanthate is considered one of the milder anabolic steroids, but it is not free from side effects. Androgenic effects can include acne, oily skin, and hair loss in individuals predisposed to male pattern baldness. Lipid profile monitoring is relevant as anabolic steroids can decrease HDL cholesterol by 20% to 70% and increase LDL cholesterol by approximately 36% to over 100%, with effects being dose and duration-dependent.
Methenolone enanthate suppresses endogenous testosterone production, and running it without a sufficient testosterone base can lead to symptoms of low testosterone. Post-cycle therapy is commonly recommended after a cycle.
Methenolone enanthate suppresses the hypothalamic-pituitary-gonadal axis, and post-cycle therapy is commonly recommended after a cycle. Agents such as Clomiplex (clomiphene citrate) and Tamoxiplex (tamoxifen citrate) are frequently referenced for this purpose. Due to the long enanthate ester, PCT should typically begin approximately 2 weeks after the final injection to allow for ester clearance.
Dosing strategies and support protocols should account for individual experience and health status. The information above is for educational reference and does not constitute medical advice.
Methenolone enanthate is an anabolic steroid with androgenic and cardiovascular considerations. Medical use requires appropriate diagnosis and ongoing clinical supervision.
Methenolone enanthate is an anabolic-androgenic steroid that is not approved for bodybuilding or athletic performance enhancement. It is classified as a controlled substance in many countries, and its use is banned by the World Anti-Doping Agency. Adverse reactions are more frequent with high doses and prolonged treatments.
Periodic liver function tests are recommended during medical use, and a clinically significant increase in liver function parameters or the appearance of cholelithiasis requires suspension of treatment. Regular prostate examinations are recommended in men.
Methenolone enanthate is not approved for bodybuilding or athletic performance enhancement. Non-medical use falls outside approved indications and may carry additional health risks beyond those associated with supervised medical use.
Documented adverse effects of methenolone include fluid and electrolyte retention, hypercalcaemia, increased bone growth and skeletal weight. In men, additional side effects include priapism, azoospermia, hirsutism, male pattern baldness, acne, and oedema. In women, side effects include virilization, amenorrhoea, menstrual irregularities, suppressed lactation, and increased libido.
In women with marked sensitivity to androgenic stimuli, undesirable effects due to the residual androgenic action of methenolone enanthate may rarely appear, such as acne, hirsutism, and voice changes. After the first signs of voice changes, treatment suspension is recommended.
Other reported adverse effects include nausea, vomiting, diarrhea, hypercholesterolemia, hypercalcemia, leucopenia, jaundice, and premature closure of epiphyses in adolescents. Methenolone enanthate suppresses endogenous testosterone production, which can affect libido, mood, and fertility.
Methenolone enanthate is contraindicated in pregnancy and breastfeeding due to the risk of virilization of the external genitalia of the female fetus, and in patients with prostate cancer or adenoma, acute or chronic prostatitis, breast cancer in men, severe liver damage or liver failure, ischemic heart disease, myocardial infarction, heart failure, diabetes mellitus, and hypercalcemia. Medical evaluation is required before any consideration of use. Women of childbearing age should adopt effective contraceptive measures during treatment and for some time after.
In non-medical contexts, blood work to monitor liver enzymes and lipid profiles is frequently recommended during and after cycles. Regular prostate examinations are recommended in men. These monitoring practices are not a substitute for clinical oversight, which is required for safe use of any anabolic steroid.
Store at a temperature not exceeding 25°C in a dry place protected from light and out of reach of children. Keep the vial in its original packaging until use. Do not freeze. Before administration, inspect the solution and avoid use if it appears cloudy, discolored, contains particulate matter, or if the vial or seal is compromised.
Primoplex 100 mg is shipped in original manufacturer packaging with discreet, privacy-focused handling.
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Proper storage conditions help preserve formulation stability and overall product integrity throughout shelf life.
Store at a temperature not exceeding 25°C in a dry place protected from light and out of reach of children. Keep the vial in its original packaging until use. Do not freeze. Before administration, inspect the solution and avoid use if it appears cloudy, discolored, contains particulate matter, or if the vial or seal is compromised.
Answers to common questions about Primoplex 100 mg, methenolone enanthate, dosing, and product characteristics.
Primoplex 100 mg contains methenolone enanthate, an injectable anabolic steroid. In medical practice, it has been indicated for diseases and states requiring an increase in protein production, such as consumptive diseases, cachexia, and advanced breast or genital carcinoma in women. In non-medical bodybuilding contexts, it is commonly referenced for lean muscle preservation during cutting phases, though such use falls outside approved indications.
Methenolone enanthate has a biological half-life of approximately 10.5 days following intramuscular injection. In non-medical contexts, it is typically referenced as being administered once or twice weekly to maintain stable blood levels. This is distinct from medically supervised dosing, which is individualized by a clinician.
Yes. Methenolone enanthate suppresses the hypothalamic-pituitary-gonadal axis, and post-cycle therapy is commonly recommended after a cycle. Agents such as Clomiplex or Tamoxiplex are commonly referenced for this purpose. Due to the long enanthate ester, PCT should typically begin approximately 2 weeks after the final injection.
Methenolone enanthate binds to androgen receptors in muscle tissue, increasing nitrogen retention and protein synthesis. It is a modification of dihydrotestosterone (DHT) with weak androgenic activity and a moderate anabolic effect, notable for binding firmly to androgen receptors, stronger than testosterone. It does not convert to estrogen, contributing to its reputation as a mild compound with minimal water retention.
Due to the long enanthate ester, blood levels accumulate gradually. In bodybuilding discussions, users sometimes report noticeable effects on muscle preservation and definition within the first 3–4 weeks of use at 400–600 mg per week. Full steady-state effects for the enanthate ester are typically reached by weeks 6–8. Individual response varies considerably.
There is no universally "best" injectable for cutting. Methenolone enanthate is commonly referenced for its mild profile and muscle preservation effects, but Mastaplex 100 (drostanolone propionate) and Oxandroplex (oxandrolone) are also widely discussed. The appropriate choice depends on individual goals, sensitivity to androgenic side effects, and budget.
Both are methenolone esters, but they differ in release rate and administration route. Methenolone enanthate is the injectable, long-acting form with a half-life of approximately 10.5 days, supporting once or twice weekly injections. Methenolone acetate is the oral, short-acting form with a half-life of about 4–6 hours, requiring multiple daily doses.
Both are long-acting injectable anabolic steroids, but they have different profiles. Methenolone is a DHT derivative that does not aromatize and has lower estrogenic properties than nandrolone, making it a good fat burner. Nandrolone decanoate is a 19-nor compound that can aromatize to a mild degree. Axiolabs offers Decaplex 250 as its nandrolone decanoate product.
In non-medical bodybuilding contexts, 400 mg per week is within the commonly referenced range of 400–800 mg per week for men. Primoplex 100 mg contains 100 mg/mL, so 400 mg would equal 4 mL per week. Dosage appropriateness depends on individual factors and the overall cycle context.
Primoplex 100 mg is labeled at 100 mg of methenolone enanthate per mL. It is supplied in a 10 mL vial, giving 1,000 mg of total labeled methenolone enanthate content per vial.
Lab testing information for Primoplex 100 mg is not available on this page. For product-specific testing inquiries, please contact customer support.
Methenolone is one of the few anabolic steroids tolerated by women due to its low androgenic properties, with women typically referenced at 50–100 mg per week. However, virilization symptoms including acne, hirsutism, and voice changes can occur, and treatment should be suspended at the first sign of voice changes. Women should be aware of these risks.