Melanotan 2 10 mg Melanotan 2 10 mg
Peptide Hubs

Melanotan 2 10 mg

Product Information Compound Details
Peptide Hubs
Active Substance Melanotan II Synthetic alpha-MSH analog (cyclic heptapeptide)
10 mg/vial
Strength 10 mg/vial
Package 1 Vial
Form Lyophilized Powder
Vial Size 2 mL Vial
Drug Class Research Peptide
Manufacturer Peptide Hubs
Latest Laboratory Result 10.45 mg April 22, 2025 · 104.5% of label claim View
$26.40 $44.00
Shipping :
International
U.S. Domestic
You will save $17.60
Product Overview

Melanotan 2 10 mg by Peptide Hubs

Melanotan 2 10 mg is a lyophilized Melanotan II research product manufactured by Peptide Hubs and supplied as a 10 mg/vial powder in a 2 mL vial.

Melanotan II Injectable

Melanotan 2 10 mg contains Melanotan II (MT-II), a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). Melanotan II is a non-selective melanocortin receptor agonist with high affinity for multiple receptor subtypes, including MC1R, MC3R, MC4R, and MC5R. Its activation of MC1R leads to increased melanin synthesis and skin pigmentation, while effects on MC3R and MC4R are associated with appetite suppression and enhanced sexual function.

Melanotan II is not FDA-approved for any human use and its sale is illegal in all 50 U.S. states, as well as in the United Kingdom and Australia. Despite this, it is marketed online as a research chemical and used non-medically for tanning purposes. Melanotan II works by stimulating the body's production of melanin, but it still requires exposure to UV rays to produce a tan. The effect is temporary and fades when use is discontinued.

Melanotan II is associated with a long list of potential adverse effects, including nausea, facial flushing, decreased appetite, and spontaneous erections. More serious risks include priapism (painful, sustained erections that can cause permanent erectile dysfunction), renal infarction, and rhabdomyolysis (muscle breakdown that can lead to kidney failure and death). Melanotan II is also associated with melanoma, an invasive skin cancer with a high risk of death.

Key Benefits of Melanotan 2 10 mg

  • Synthetic α-MSH analog for melanocortin receptor research
  • Lyophilized powder format for reconstitution flexibility
  • Studied for MC1R-mediated melanin synthesis pathways
  • 10 mg per vial for research protocols
  • Manufactured by Peptide Hubs
Formulation

Lyophilized Powder

Melanotan 2 10 mg is supplied as a lyophilized (freeze-dried) powder in a 2 mL vial. Reconstitution with an appropriate solvent is required before use in research contexts.

Product Profile

Melanotan II Profile

Melanotan II is a synthetic cyclic heptapeptide with the molecular formula C₅₀H₆₉N₁₅O₉ and a molecular weight of approximately 1,024.2 Da. Its CAS registry number is 121062-08-6.

Melanocortin Receptor Agonist

Melanotan II belongs to the class of melanocortin receptor agonists, which are synthetic analogs of endogenous melanocyte-stimulating hormones. It is a non-selective agonist with high affinity for multiple melanocortin receptor subtypes. Binding affinity data shows Melanotan II has Ki values of 0.61 nM for MC1R, 3.9 nM for MC3R, 6.0 nM for MC4R, and 56 nM for MC5R.

Activation of MC1R on melanocytes stimulates melanin synthesis, leading to increased skin pigmentation. Effects on MC3R and MC4R are associated with appetite suppression and enhanced sexual function, which were discovered accidentally during research into skin pigmentation effects. Melanotan II works at the level of the brain for its sexual effects, eliciting a natural sexual response.

Melanotan II has a short half-life and requires frequent administration in non-medical protocols. It is associated with rapid receptor desensitization and a long list of adverse effects, including potentially life-threatening conditions.

Defining Characteristic

Non-Selective Melanocortin Agonism

Melanotan II is distinguished by its non-selective activation of multiple melanocortin receptor subtypes (MC1R, MC3R, MC4R, MC5R), which produces both its tanning effects and its broader systemic effects including appetite suppression and sexual arousal.

Melanotan 2 10 mg vs Other Peptide Hubs Preparations

Peptide Hubs offers several research peptides targeting different biological systems. Within this lineup, PT-141 is a related melanocortin agonist (bremelanotide) that is an active metabolite of Melanotan II, with receptor selectivity shifted more toward MC3R and MC4R and reduced impact on pigmentation.

For research focused on tissue repair rather than melanocortin signaling, BPC 157 represents a different approach entirely, operating through angiogenic and cytoprotective mechanisms. For research requiring a reconstitution solution, Bacteriostatic Water is the standard diluent for preparing lyophilized peptides like Melanotan 2 10 mg.

Laboratory Testing

Melanotan 2 10 mg Lab Reports

Published laboratory reports for Melanotan 2 10 mg are shown below with the test date and measured content.

Melanotan 2 10 mg by Peptide Hubs lab report dated April 22, 2025 showing 10.45 mg View Report
April 22, 2025
Measured Result 10.45 mg 104.5% of label claim
Label 10 mg
Difference +0.45 mg

Laboratory results apply to the specific tested sample represented in each published report and should not be interpreted as a measurement of every vial or production batch.

Dosage & Usage

Melanotan 2 10 mg Dosage & Usage

The information below is provided for educational reference only. Melanotan II is not an FDA-approved human drug and its sale is illegal in the United States. Its use for any purpose falls outside approved indications, and no established human dosing regimen exists.

Typical Dosage Ranges

Because Melanotan II lacks FDA approval and published human dose-finding trials, there is no medically established dosage range. Non-medical community protocols reference weight-based dosing, though these are anecdotal and not evidence-based. A commonly referenced conservative approach starts at 0.0125 mg/kg as a true starting dose, escalating to 0.025 mg/kg after observing initial response.

Use Case Common Reference Range Injection Frequency
Conservative start (community) 50–75 mcg Every other day, only on tanning days
Weight-based start (community) 0.0125 mg/kg Every other day
Full calculated dose (community) 0.025 mg/kg Every other day

Community protocols emphasize starting at very low doses (50–75 mcg) and tapering slowly, with administration only on days when UV exposure will follow within an hour. Higher doses (500 mcg–1 mg) are associated with significantly increased risk of nausea, freckling, and new moles.

Reconstitution & Handling

Melanotan 2 10 mg is supplied as a lyophilized powder and requires reconstitution before use. A 10 mg vial reconstituted with 3 mL of bacteriostatic water yields a concentration of approximately 3.33 mg/mL (3,333 mcg/mL). At this concentration, a 250 mcg dose would require drawing approximately 7.5 units on a U-100 insulin syringe.

Reconstituted solution should be stored refrigerated at 2–8°C and protected from light. Avoid vigorous shaking during reconstitution to reduce foaming.

Stacking & Cycle Considerations

Melanotan II is not typically stacked with other peptides in non-medical contexts. Community protocols emphasize administration only on days of UV exposure, within an hour before tanning. Administration without concurrent UV exposure is reported to increase the risk of uneven pigmentation and side effects in areas with high natural melanocyte activity, such as genitals and existing freckles.

There is no established cycling protocol for Melanotan II. Non-medical use is generally discontinued when the desired tan is achieved, with some users maintaining with occasional low-dose injections.

Important

Individual Response Varies

No human dose-response data for therapeutic outcomes exists for Melanotan II. All dosage information is derived from community convention and should not be interpreted as medical guidance.

Safety & Information

Melanotan II Safety Information

Melanotan II is not FDA-approved for any human use and its sale is illegal in all 50 U.S. states, as well as in the United Kingdom and Australia. It is associated with serious and potentially life-threatening health risks.

Important Safety Information

Melanotan II is completely synthetic and is not approved by the FDA. Because the FDA does not regulate Melanotan II products, users cannot be sure what is in them regardless of label claims. One study found that the actual amount of Melanotan II in vials ranged from 4.32 to 8.84 mg, although sellers claimed each vial contained 10 mg.

Melanotan II products are sometimes marketed as a way to protect from skin cancer, but the opposite is true: they increase sun sensitivity and exposure, and are associated with melanoma.

Important

Non-Medical Use

Melanotan II is sold as a research chemical but is not approved for any human indication. Non-medical use falls outside approved indications and carries documented serious risks including priapism, renal infarction, and rhabdomyolysis.

Potential Adverse Effects

Melanotan II comes with a long list of possible side effects, including: acne, decreased appetite, gastrointestinal issues including diarrhea and vomiting, nausea, facial flushing (redness), and spontaneous erections.

More serious risks include: priapism (painful, sustained erections that can cause scarring and permanent erectile dysfunction), renal infarction (a rare but life-threatening condition that causes reduced blood flow to the kidneys), and rhabdomyolysis (a condition in which muscle cells disintegrate, which can lead to acute kidney injury and even death). Melanotan II can cause a sudden increase in moles and freckles, and it is associated with melanoma, an invasive skin cancer with a high risk of death.

Conditions Requiring Medical Evaluation

Given the serious and potentially life-threatening risks associated with Melanotan II, any consideration of its use should involve consultation with a qualified healthcare professional. Individuals with a history of melanoma or skin cancer, cardiovascular conditions, or kidney disease should exercise extreme caution.

Monitoring During Use

No established monitoring protocol exists for non-medical Melanotan II use. Any adverse reactions should be documented and reported to appropriate authorities.

Product Care

Storage & Handling

Store lyophilized powder at -20°C, sealed, dry, and protected from light. Once reconstituted, store refrigerated at 2–8°C and use within the recommended timeframe. Avoid vigorous shaking during reconstitution. Keep out of reach of children.

Shipping & Authenticity

Shipping & Product Authenticity

Melanotan 2 10 mg is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging with discreet handling.

USA Domestic 3–5 business days
International 10–15 business days
Order Processing 24–48 business hours
Tracking Provided after dispatch
Direct Supply

Discreet Delivery & Original Packaging

The outer shipping package remains discreet, with privacy-focused handling. Products are supplied through the official Peptide Hubs distribution chain.

What to Expect

  • Orders are processed after payment confirmation
  • USA Domestic shipping is typically faster when local stock is selected
  • International orders include tracking, though update frequency may vary
  • Multiple warehouses may result in separate shipments when applicable

Authenticity Verification

To verify your Melanotan 2 10 mg product, use the security code on the vial label and cross-check it on the Peptide Hubs official site. Original packaging and manufacturer presentation help reinforce product legitimacy.

For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.

Storage

Melanotan 2 10 mg Storage

Proper storage conditions help preserve peptide stability and integrity throughout shelf life.

Recommended Conditions

Store lyophilized powder at -20°C, sealed, dry, and protected from light. Under these conditions, the dry powder is stable for extended periods.

Once reconstituted, store refrigerated at 2–8°C and protected from light. Avoid repeated freeze-thaw cycles to maintain peptide integrity.

Keep out of reach of children. Follow proper handling practices.

Quick Reference

Do & Don't

  • Do store powder at -20°C, sealed and protected from light
  • Do keep in original packaging until use
  • Do refrigerate reconstituted solution at 2–8°C
  • Don't expose to excessive heat or moisture
  • Don't subject to repeated freeze-thaw cycles
  • Don't use if solution appears cloudy or contains particles
Frequently Asked Questions

Melanotan 2 10 mg FAQ

Answers to common questions about Melanotan 2 10 mg, Melanotan II, and research peptide handling.

What is Melanotan 2 10 mg used for?

Melanotan 2 10 mg contains Melanotan II, a synthetic α-MSH analog studied in research for its effects on melanocortin receptors. In non-medical contexts, it is used for tanning purposes, though such use is illegal in the United States and associated with serious health risks.

How often should Melanotan 2 10 mg be injected?

No established human dosing schedule exists. Community protocols emphasize administration only on days of UV exposure, within an hour before tanning, typically every other day. This is based on convention, not clinical data.

Does Melanotan 2 10 mg require PCT?

Melanotan II does not suppress endogenous testosterone production and does not require post-cycle therapy in the way anabolic steroids do. However, any non-medical peptide use should be approached with extreme caution given the documented serious risks including priapism, renal infarction, and rhabdomyolysis.

What does Melanotan II do?

Melanotan II is a non-selective melanocortin receptor agonist that activates MC1R (melanin synthesis), MC3R, MC4R (appetite suppression and sexual function), and MC5R. Its tanning effects require concurrent UV exposure to work.

How long does Melanotan II take to work?

The tanning effect only lasts as long as Melanotan II is used. When use stops, melanin levels decrease and the tan fades. Community reports suggest visible darkening within 1–3 weeks with regular administration and UV exposure.

Is Melanotan II the best tanning peptide?

There is no universally “best” tanning peptide, and Melanotan II is not FDA-approved for any use. It is illegal to sell in the United States and is associated with serious health risks including melanoma.

What is the difference between Melanotan 2 10 mg and PT-141?

Melanotan II and PT-141 (bremelanotide) are both melanocortin agonists, but PT-141 is an active metabolite of Melanotan II with reduced impact on pigmentation and more selectivity toward MC3R and MC4R. They are not interchangeable.

What is the difference between Melanotan 2 10 mg and BPC 157?

Melanotan II targets melanocortin receptors for pigmentation and related effects, while BPC 157 is a tissue-repair peptide studied for angiogenic and cytoprotective effects. They operate through entirely different mechanisms and address different biological goals.

Is 500 mcg of Melanotan II a lot?

500 mcg is considered a high dose in community discussions and is associated with significantly increased risk of nausea, freckling, and new moles. Conservative protocols recommend starting at 50–75 mcg and tapering slowly.

What strength is Melanotan 2 10 mg?

Melanotan 2 10 mg is labeled at 10 mg of Melanotan II per vial. It is supplied as a lyophilized powder in a 2 mL vial.

Is Melanotan 2 10 mg lab tested?

Yes. A published laboratory report dated April 22, 2025 measured Melanotan 2 10 mg at 10.45 mg, equivalent to 104.5% of its 10 mg label claim. However, because Melanotan II products are not FDA-regulated, users cannot be sure what is in them regardless of label claims.

How should Melanotan 2 10 mg be stored?

Store the lyophilized powder at -20°C, sealed, dry, and protected from light. Once reconstituted, refrigerate at 2–8°C and protect from light. Avoid repeated freeze-thaw cycles.

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