Sexual Health
Kalpa Pharmaceuticals
Sildenaxyl 100 mg
Product Information Compound Details
Active Substance Sildenafil Citrate PDE5 inhibitor for erectile dysfunction
100 mg/tabletStrength 100 mg/tablet
Package 20 or 100 Tablets 2,000 mg or 10,000 mg total labeled content
Form Oral Tablet
Half-Life Approximately 4 Hours
Drug Class Phosphodiesterase-5 Inhibitor
Manufacturer Kalpa Pharmaceuticals
Amount :
20 tabs
100 tabs
Shipping :
International
U.S. Domestic
Out of stock
- Overview
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Product Overview
Sildenaxyl 100 mg by Kalpa Pharmaceuticals
Sildenaxyl 100 mg is an oral sildenafil citrate tablet manufactured by Kalpa Pharmaceuticals and dosed at 100 mg per tablet, available in packs of 20 or 100 tablets.
Sildenafil Citrate Oral
Sildenaxyl 100 mg contains sildenafil citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Sildenafil is FDA-approved for the treatment of erectile dysfunction (ED), which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. In order for sildenafil to be effective, sexual stimulation is required.
The mechanism of action involves inhibition of PDE5, which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of nitric oxide, sildenafil inhibits PDE5 and increases cGMP levels, resulting in smooth muscle relaxation and increased blood flow to the penis. Sildenafil is rapidly absorbed, with peak plasma concentrations occurring 30 to 120 minutes after oral administration.
The recommended dose for most patients is 50 mg taken as needed approximately 1 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day. Sildenafil is contraindicated in patients taking organic nitrates in any form due to the risk of potentially fatal hypotension.
Key Benefits of Sildenaxyl 100 mg
- FDA-approved for the treatment of erectile dysfunction
- Selective PDE5 inhibitor that enhances erectile response with sexual stimulation
- Rapid onset of action, typically within 30–60 minutes
- Effects generally last for approximately 4 hours
- Manufactured by Kalpa Pharmaceuticals with original packaging
Oral Formulation
Compressed Tablet
Sildenaxyl 100 mg is supplied as an oral compressed tablet containing 100 mg of sildenafil citrate per unit, packaged in 20-tablet or 100-tablet formats by Kalpa Pharmaceuticals.
Product Profile
Sildenafil Citrate Profile
Sildenafil citrate is a selective PDE5 inhibitor characterized by rapid absorption, a half-life of approximately 4 hours, and dependence on sexual stimulation for efficacy. Its profile distinguishes it from other erectile dysfunction treatments.
Phosphodiesterase-5 Inhibitor
Sildenafil citrate is a selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), the enzyme responsible for degradation of cGMP in the corpus cavernosum. Inhibition of PDE5 increases cGMP levels, which leads to smooth muscle relaxation and increased blood flow to the penis during sexual stimulation. Sildenafil is only about 10-fold as potent for PDE5 compared to PDE6, an enzyme in the retina; this lower selectivity is thought to be the basis for abnormalities related to color vision.
Sildenafil is rapidly absorbed after oral administration, with a mean absolute bioavailability of 41%. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. The terminal half-life is approximately 4 hours. Sildenafil is extensively metabolized in the liver, primarily by CYP3A4, with CYP2C9 also contributing.
The efficacy of sildenafil requires sexual stimulation to initiate the nitric oxide/cGMP cascade. The recommended dose is 50 mg taken as needed approximately 1 hour before sexual activity, with the dose possibly increased to a maximum of 100 mg or decreased to 25 mg based on effectiveness and toleration.
Release Profile
Intermediate Half-Life
Sildenafil has a terminal half-life of approximately 4 hours. The effects generally last for about 4 hours, with the first two hours typically being the most effective window.
Sildenaxyl 100 mg vs Other Kalpa Preparations
Kalpa Pharmaceuticals offers a range of compounds for men's health. For those comparing erectile dysfunction treatments, Taldenaxyl (tadalafil) is a longer-acting PDE5 inhibitor. Other products such as Arimixyl 1 mg (anastrozole) and Nolvaxyl 20 mg (tamoxifen) are not intended for erectile dysfunction but are sometimes referenced in non-medical bodybuilding contexts for managing hormonal side effects associated with anabolic steroid use.
Dosage & Usage
Sildenaxyl 100 mg Dosage & Usage
The information below is provided for educational reference only. Sildenafil citrate is a prescription medication; medical use requires appropriate diagnosis, clinical supervision, and ongoing monitoring. Non-medical use falls outside approved indications.
Typical Dosage Ranges
In FDA-approved medical use, the recommended dose of sildenafil for most patients is 50 mg taken as needed approximately 1 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day. For patients over 65 years, patients with hepatic impairment, or patients with severe renal impairment, a starting dose of 25 mg should be considered.
| Use Case | Common Reference Range | Frequency |
|---|---|---|
| Medical (standard starting dose) | 50 mg per dose | As needed, ~1 hour before activity |
| Medical (maximum dose) | 100 mg per dose | Once daily maximum |
| Medical (elderly, hepatic/renal impairment) | 25 mg starting dose | As needed |
| Medical (with CYP3A4 inhibitors) | 25 mg starting dose | As needed |
Stacking & Cycle Considerations
Sildenafil is not typically used in cycles or stacked with other compounds in the way anabolic steroids are. It is used on an as-needed basis for erectile dysfunction. In non-medical bodybuilding contexts, sildenafil may be referenced by individuals using anabolic steroids who experience erectile dysfunction as a side effect of hormonal fluctuations, though such use falls outside approved indications.
It is important to note that sildenafil is contraindicated with organic nitrates. Patients should inform their healthcare provider about all medications they are taking, including prescription and non-prescription medicines, vitamins, and herbal products.
Managing Side Effects
The most common side effects with sildenafil include headache, flushing, upset stomach, nasal congestion, and visual changes (including color tinge and increased sensitivity to light). These effects are generally mild and transient.
Serious but rare adverse effects include non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including permanent loss of vision, and sudden decrease or loss of hearing. Priapism (erections lasting more than 4 hours) requires immediate medical attention.
Important
Individual Response Varies
Dosing strategies should be adjusted based on individual response and medical guidance. The information above is for educational reference and does not constitute medical advice.
Safety & Information
Sildenafil Citrate Safety Information
Sildenafil citrate is a prescription medication with vasodilatory effects, potential cardiovascular interactions, and specific contraindications. Medical use requires appropriate diagnosis, clinical supervision, and ongoing monitoring.
Important Safety Information
Sildenafil is contraindicated in patients taking organic nitrates in any form (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate) due to the risk of potentially fatal hypotension. Sildenafil is also contraindicated in patients with known hypersensitivity to sildenafil or any component of the formulation.
Before prescribing sildenafil, healthcare providers should carefully consider whether patients with underlying conditions could be adversely affected by the vasodilatory effects, including patients on antihypertensive therapy or with resting hypotension (blood pressure less than 90/50), fluid depletion, severe left ventricular outflow obstruction, or autonomic dysfunction.
Important
Non-Medical Use
Sildenafil is a prescription medication. Non-medical use is not approved by the FDA and may be associated with serious health risks, particularly in individuals with underlying cardiovascular conditions or those taking nitrate medications.
Potential Adverse Effects
The most common adverse reactions (occurring in ≥2% of patients) include headache, flushing, dyspepsia, nasal congestion, urinary tract infection, abnormal vision, diarrhea, dizziness, and rash. Visual changes including color tinge, increased sensitivity to light, and blurred vision have been reported.
Serious adverse events reported post-marketing include serious cardiovascular, cerebrovascular, and vascular events (including myocardial infarction, sudden cardiac death, ventricular arrhythmia, cerebrovascular hemorrhage, and transient ischemic attack), non-arteritic anterior ischemic optic neuropathy (NAION), sudden decrease or loss of hearing, and priapism. Most, but not all, of the cardiovascular events occurred in patients with preexisting cardiovascular risk factors.
Sildenafil may potentiate the hypotensive effects of nitrates and alpha-blockers. When co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating sildenafil, and sildenafil should be initiated at 25 mg.
Conditions Requiring Medical Evaluation
Patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronie's disease) or conditions that may predispose them to priapism (such as sickle cell anemia, multiple myeloma, or leukemia) should use sildenafil with caution.
Use of sildenafil in patients with retinitis pigmentosa is not recommended due to a minority of patients having genetic disorders of retinal phosphodiesterases. The safety of sildenafil is unknown in patients with bleeding disorders or active peptic ulceration.
Monitoring During Therapy
Patients should be advised to seek immediate medical attention in the event of a sudden loss of vision in one or both eyes or sudden decrease or loss of hearing while taking sildenafil. If an erection persists longer than 4 hours, the patient should seek immediate medical assistance to prevent penile tissue damage and permanent loss of potency.
Blood pressure should be monitored when co-administering blood pressure-lowering drugs with sildenafil.
Product Care
Storage & Handling
Store in a cool, dry place away from direct light and moisture. Keep tablets in the original packaging until use. Keep out of reach of children.
Further Safety Information
Shipping & Authenticity
Shipping & Product Authenticity
Sildenaxyl 100 mg is supplied through the official Kalpa Pharmaceuticals distribution chain and shipped in original manufacturer packaging with discreet, privacy-focused handling.
USA Domestic 3–5 business days
International 10–15 business days
Order Processing 24–48 business hours
Tracking Provided after dispatch
Direct Supply
Discreet Delivery & Original Packaging
The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details. Products are supplied through the official Kalpa Pharmaceuticals distribution chain.
What to Expect
- Orders are processed after payment confirmation
- USA Domestic shipping is typically faster when local stock is selected
- International orders include tracking, though update frequency may vary by destination
- Multiple warehouses may result in separate shipments when applicable
Authenticity Verification
To verify your Sildenaxyl 100 mg product, use the security code on the packaging and cross-check it on the Kalpa official site. Original Kalpa Pharmaceuticals presentation and packaging help reinforce product legitimacy and buyer confidence.
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Storage
Sildenaxyl 100 mg Storage
Proper storage conditions help preserve tablet integrity and stability throughout shelf life.
Recommended Conditions
Store Sildenaxyl 100 mg in a cool, dry place away from excessive heat, moisture, and direct light. Maintaining stable conditions helps preserve the integrity of the tablets.
Keep the tablets in their original packaging until use. Do not use if the packaging is damaged or if the tablets appear abnormal in color or texture.
Keep out of reach of children. Follow proper handling practices for oral medications.
Quick Reference
Do & Don't
- Do store in a cool, dry place
- Do keep in original packaging
- Do inspect tablets before use
- Don't expose to direct sunlight
- Don't store in humid environments
- Don't use if packaging is compromised
Frequently Asked Questions
Sildenaxyl 100 mg FAQ
Answers to common questions about Sildenaxyl 100 mg, sildenafil citrate, dosing, side effects, and product specifications.
What is Sildenaxyl 100 mg used for?
Sildenaxyl 100 mg contains sildenafil citrate, which is FDA-approved for the treatment of erectile dysfunction (ED), defined as the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. In order for sildenafil to be effective, sexual stimulation is required.
How often should Sildenaxyl 100 mg be taken?
Sildenafil is taken as needed approximately 1 hour before sexual activity. The maximum recommended dosing frequency is once per day. The recommended starting dose is 50 mg, which may be increased to a maximum of 100 mg or decreased to 25 mg based on effectiveness and toleration.
Does Sildenaxyl 100 mg require PCT?
Sildenafil is not a hormonal compound and does not suppress the hypothalamic-pituitary-gonadal axis. Therefore, post-cycle therapy (PCT) is not applicable. If sildenafil is used alongside suppressive anabolic compounds, standard PCT protocols should be followed for those compounds.
What does sildenafil do for a man?
Sildenafil inhibits PDE5, which increases cGMP levels in the corpus cavernosum during sexual stimulation. This leads to smooth muscle relaxation and increased blood flow to the penis, facilitating erection. It does not cause erection without sexual stimulation.
How long does it take for sildenafil to fully kick in?
Sildenafil typically starts working within 30 to 60 minutes of taking a tablet. Peak concentration in the bloodstream occurs at around the one-hour mark. Taking it after a large, high-fat meal can delay absorption by up to an hour. The effects generally last for approximately 4 hours.
Is sildenafil as strong as Viagra?
Viagra is a brand name for sildenafil citrate. Generic sildenafil contains the same active ingredient and is considered therapeutically equivalent to the brand version. Sildenaxyl 100 mg contains 100 mg of sildenafil citrate, which is the maximum recommended dose.
What are the downsides of sildenafil?
Common side effects include headache, flushing, dyspepsia, nasal congestion, and visual changes. Serious but rare risks include non-arteritic anterior ischemic optic neuropathy (NAION), sudden hearing loss, and priapism. Sildenafil is contraindicated with organic nitrates due to the risk of severe hypotension.
What is the difference between sildenafil and tadalafil?
Both sildenafil and tadalafil are PDE5 inhibitors used for erectile dysfunction. The main difference is duration of action: sildenafil lasts approximately 4 to 5 hours, while tadalafil has a longer duration and is also approved for daily use. Sildenafil has a more rapid onset for as-needed use, while tadalafil offers greater spontaneity due to its longer window of activity.
Is 100 mg of sildenafil a lot?
A 100 mg tablet represents the maximum recommended single dose of sildenafil. The standard starting dose is 50 mg, and the dose may be increased to 100 mg or decreased to 25 mg based on effectiveness and toleration. Higher doses do not necessarily work faster but may produce a stronger effect.
What strength is Sildenaxyl 100 mg?
Sildenaxyl 100 mg is labeled at 100 mg of sildenafil citrate per tablet. It is supplied in packs of 20 or 100 tablets.
Is Sildenaxyl 100 mg lab tested?
Laboratory testing information for Sildenaxyl 100 mg is not currently available in this product listing. Kalpa Pharmaceuticals products are manufactured under pharmaceutical-grade conditions, but independent lab reports are not published for this specific product at this time.
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Drug Class
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