S4 25 mg
Dragon Pharma

S4 25 mg

Product Information Compound Details
Dragon Pharma
Active Substance Andarine Selective Androgen Receptor Modulator (SARM)
25 mg/tablet
Strength 25 mg/tablet
Package 100 Tablets 2,500 mg total labeled content
Form Oral Tablet
Half-Life Approximately 4 Hours
Drug Class SARM
Manufacturer Dragon Pharma
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International
U.S. Domestic
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Product Overview

S4 25 mg by Dragon Pharma

S4 25 mg is an oral andarine tablet manufactured by Dragon Pharma and dosed at 25 mg per tablet in a 100-tablet package.

Andarine Oral

S4 25 mg contains andarine (S-4), a nonsteroidal selective androgen receptor modulator (SARM). Andarine was first characterized as the lead compound in the arylpropionamide class of SARMs, demonstrating potent androgen receptor binding affinity with tissue-selective androgenic and anabolic effects in preclinical models. It was designed to be orally active with anabolic effects on muscle and bone, but lesser activity in prostate and seminal vesicles compared to traditional androgens.

In animal studies, andarine showed dose-dependent effects in the levator ani muscle that were similar in potency and efficacy to testosterone propionate, while only partially restoring prostate and seminal vesicle weights. This tissue selectivity is the defining feature of the SARM class. Andarine is not approved by the FDA for any human indication and is classified as an unapproved new drug when sold for human consumption. The FDA has issued warning letters to companies selling andarine, citing safety concerns including life-threatening reactions and liver toxicity.

In non-medical bodybuilding and fitness contexts, andarine is commonly referenced for lean muscle preservation during cutting phases and for potential bone density support. It is prohibited by the World Anti-Doping Agency (WADA) at all times, and its metabolites are well-characterized for doping control purposes. Non-medical use falls outside approved indications and carries health risks including hormonal suppression, potential liver injury, and a distinctive visual side effect profile.

Key Benefits of S4 25 mg

  • Tissue-selective SARM with anabolic effects on muscle and bone
  • Oral bioavailability for convenient administration
  • Commonly referenced for lean muscle preservation during cutting
  • Half-life of approximately 4 hours supports split dosing
  • 25 mg tablet strength for flexible dosing
Product Profile

Andarine Profile

Andarine (S-4) is a nonsteroidal SARM from the arylpropionamide class, characterized by potent androgen receptor binding, tissue selectivity for muscle and bone, and a relatively short half-life in preclinical models.

Arylpropionamide SARM

Andarine is structurally classified as an arylpropionamide SARM, a class of nonsteroidal compounds designed to selectively activate androgen receptors in anabolic tissues. In castrated male rats, andarine demonstrated dose-dependent effects in the levator ani muscle (an androgen-responsive muscle) that were similar in potency and efficacy to testosterone propionate, while only restoring prostate and seminal vesicles to approximately 34% and 28% of intact animals, respectively.

The pharmacokinetics of andarine have been studied in animal models. In rats, the half-life of S-4 was determined to be between 2.6 and 5.3 hours across the dose range tested, with oral bioavailability that was dose-dependent and complete at lower doses. A separate equine study found that S-4 could be detected in plasma for only 12 hours after administration, with peak concentrations in the first sample at 5 minutes. These pharmacokinetic data support multiple daily dosing in research contexts.

Andarine's tissue selectivity is its defining pharmacological feature. Unlike traditional anabolic steroids that activate androgen receptors throughout the body, andarine was engineered to preferentially target muscle and bone while having weaker effects on reproductive tissues. However, andarine is not completely selective, and its activity at androgen receptors in other tissues, including the eye, explains its distinctive visual side effect profile.

Defining Characteristic

Tissue-Selective SARM with Short Half-Life

Andarine is distinguished by its tissue-selective anabolic activity and a half-life of approximately 4 hours in preclinical models. This short half-life supports split dosing to maintain stable blood levels.

S4 25 mg vs Other Dragon Pharma Preparations

Dragon Pharma offers multiple compounds discussed in bodybuilding and performance contexts. Andarine's SARM mechanism contrasts with anabolic steroids such as Anavar 50 or Winstrol 50, which act as full androgen receptor agonists and carry 17-alpha-alkylation or injectable administration. It is also distinct from other SARMs such as MK 2866 (ostarine), which has a longer half-life and different selectivity profile, and S 23, which is significantly more potent and suppressive. RAD 140 is another SARM often compared to andarine, though community discussion generally places RAD-140 in a lower potency tier.

The distinction between S4 and these compounds is primarily one of tissue selectivity, half-life, and the presence of distinctive visual side effects that are unique to andarine among SARMs.

Dosage & Usage

S4 25 mg Dosage & Usage

The information below is provided for educational reference only. Andarine is not approved by the FDA for any human indication and is classified as an unapproved new drug when sold for human consumption. Non-medical use falls outside approved indications and carries health risks.

Typical Dosage Ranges

No safe or effective dosage has been established for humans. In non-medical bodybuilding and fitness contexts, andarine is commonly referenced in the range of 25–75 mg per day, with split dosing due to the short half-life. Some users reference doses as high as 50–60 mg per day during cutting phases. Cycle duration is commonly referenced as 6–8 weeks.

Use Case Common Reference Range Frequency
Beginner (non-medical) 25–50 mg / day Split into 2–3 doses
Intermediate (non-medical) 50 mg / day Split into 2–3 doses
Advanced (non-medical) 50–75 mg / day Split into 2–3 doses
Cycle duration (non-medical) 6–8 weeks Due to suppression risk

Stacking & Cycle Considerations

In non-medical contexts, andarine is frequently referenced as a standalone compound for cutting phases or as an adjunct to other SARMs. It may be combined with MK 2866 (ostarine) or GW501516 for body composition goals. Stacking multiple SARMs has not been evaluated in clinical trials and increases the risk of unknown interactions and cumulative side effects. Cycle duration is commonly referenced as 6–8 weeks, with longer cycles potentially increasing suppression and side effect risk.

Managing Side Effects

Andarine's most distinctive side effect is visual disturbance, commonly described as a yellow tint to vision, particularly in low-light conditions, and difficulty adjusting between light and dark environments. This effect is dose-dependent, appears related to andarine binding to receptors in the eye, and is typically reversible after stopping the compound. Some users lower the dose, split dosing more frequently, or take andarine earlier in the day to mitigate night vision issues.

Hormonal suppression can occur, particularly at higher doses or with longer cycles. Users may experience fatigue, reduced libido, and mood changes. Liver enzyme elevation has been reported with SARM use, including andarine, and liver damage is a serious potential side effect. Bloodwork including liver function tests and lipid panel is recommended before, during, and after use.

Post-Cycle Therapy (PCT)

Andarine can suppress endogenous testosterone production, though the degree of suppression is generally considered milder than more potent SARMs like S-23 or RAD-140. In non-medical contexts, post-cycle therapy may be recommended to help restore natural hormone function. Agents such as Clomid or Nolvadex are commonly referenced for this purpose.

Important

Individual Response Varies

Andarine is not approved for human use. The information above is for educational reference and does not constitute medical advice. Non-medical use is strongly cautioned against.

Safety & Information

Andarine Safety Information

Andarine is not approved by the FDA for any human indication. The FDA has issued warning letters regarding the sale of andarine products, citing safety concerns including life-threatening reactions and liver toxicity.

Important Safety Information

Andarine (S-4) is an investigational SARM that has not been approved by the FDA for any human indication. Products marketed as andarine are considered unapproved new drugs when sold for human consumption. The FDA has determined that andarine is excluded from the dietary supplement definition, meaning it cannot legally be marketed as a dietary supplement.

Andarine is prohibited by WADA at all times, and its metabolites are well-characterized for doping control purposes. Athletes subject to drug testing should be aware that andarine is detectable and prohibited.

Important

Non-Medical Use

Andarine has no approved human indication. Non-medical use falls outside approved indications and carries health risks including hepatotoxicity, hormonal suppression, visual disturbances, and cardiovascular concerns. Product strength and laboratory verification do not establish safety for human consumption.

Potential Adverse Effects

Visual disturbances: Andarine's most distinctive side effect is visual disturbance, commonly described as a yellow tint to vision, particularly in low-light conditions, and difficulty with night vision. This effect is dose-dependent and typically reversible after stopping the compound. The mechanism is thought to involve andarine binding to receptors in the eye.

Hormonal suppression: Andarine can suppress endogenous testosterone production, with the degree depending on dose and cycle duration. Users may experience fatigue, reduced libido, and mood changes.

Liver injury: The FDA has issued warning letters citing liver toxicity concerns with SARMs, including andarine. A case report documented severe cholestatic drug-induced liver injury in a patient who used a supplement containing RAD-140 and andarine (S4). Liver damage is a serious potential side effect of andarine use.

Cardiovascular concerns: The FDA has stated that SARMs have the potential to increase the risk of heart attack and stroke.

Other reported effects: Sleep problems, upset stomach, and fertility problems have been reported with andarine use.

Conditions Requiring Medical Evaluation

Given the potential for liver injury and cardiovascular effects, any consideration of andarine exposure warrants comprehensive medical evaluation including liver function tests, lipid panel, and hormonal assessment. Individuals with pre-existing liver disease, cardiovascular disease, or hormone-sensitive conditions are at heightened risk. Women should be particularly cautious due to the potential for virilization effects, though andarine's tissue selectivity may reduce this risk compared to traditional androgens.

Monitoring During Therapy

There is no established monitoring protocol for non-medical andarine use. For any human exposure, liver function tests, lipid panel, testosterone levels, and general health assessment should be considered by a qualified healthcare professional. Bloodwork is recommended before, during, and after use.

Product Care

Storage & Handling

Store in a cool, dry place away from direct light and moisture. Keep the product in its original packaging and out of the reach of children. This product is not for human consumption.

Further Safety Information
Shipping & Authenticity

Shipping & Product Authenticity

S4 25 mg is supplied through the Dragon Pharma distribution chain and shipped in original manufacturer packaging with discreet, privacy-focused handling.

USA Domestic 3–5 business days
International 10–15 business days
Order Processing 24–48 business hours
Tracking Provided after dispatch
Direct Supply

Discreet Delivery & Original Packaging

The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details. Products are supplied through the Dragon Pharma distribution chain.

What to Expect

  • Orders are processed after payment confirmation
  • USA Domestic shipping is typically faster when local stock is selected
  • International orders include tracking, though update frequency may vary by destination
  • Multiple warehouses may result in separate shipments when applicable

Authenticity Verification

To verify your S4 25 mg product, cross-check the security features on the packaging against Dragon Pharma's official presentation. Original packaging helps reinforce product legitimacy.

For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.

Storage

S4 25 mg Storage

Proper storage conditions help preserve tablet integrity and overall product stability throughout shelf life.

Recommended Conditions

Store in a cool, dry place away from excessive heat, moisture, and direct light. Maintaining stable conditions helps preserve the integrity of the tablets.

Keep the tablets in their original packaging until use. Do not use if the packaging appears compromised or if the tablets show signs of degradation such as discoloration or crumbling.

Keep out of reach of children. This product is not for human consumption.

Quick Reference

Do & Don't

  • Do store in a cool, dry place
  • Do keep in original packaging
  • Do inspect tablets before use
  • Don't expose to direct sunlight
  • Don't store in humid environments
  • Don't use if tablets appear abnormal
Frequently Asked Questions

S4 25 mg FAQ

Answers to common questions about S4 25 mg, andarine, SARM mechanisms, dosing, and safety.

What is S4 25 mg used for?

S4 25 mg contains andarine, a SARM. It has no approved medical use. In non-medical bodybuilding and fitness contexts, it is commonly referenced for lean muscle preservation during cutting phases and for potential bone density support, though such use falls outside approved indications and carries health risks.

How often should S4 25 mg be taken?

Andarine has a half-life of approximately 4 hours in preclinical models, which supports split dosing 2–3 times daily to maintain stable blood levels. In non-medical contexts, it is typically referenced as being taken in divided doses throughout the day.

Does S4 25 mg require PCT?

Andarine can suppress endogenous testosterone production, though the degree is generally considered milder than more potent SARMs. In non-medical contexts, post-cycle therapy may be recommended to help restore natural hormone function. Agents such as Clomid or Nolvadex are commonly referenced for this purpose.

What does andarine do?

Andarine is a nonsteroidal SARM that binds the androgen receptor with tissue selectivity for muscle and bone. In animal studies, it demonstrated anabolic effects in the levator ani muscle similar to testosterone propionate while having weaker effects on prostate and seminal vesicles. It is not approved for human use.

How long does S4 take to work?

In non-medical contexts, users often report noticeable effects on muscle hardness and vascularity within the first 2–3 weeks of use. Body composition changes develop over a 6–8 week cycle. However, these reports are anecdotal and no controlled human trials have established efficacy or onset time.

Is andarine the best SARM?

There is no universally "best" SARM. Andarine is distinguished by its tissue selectivity and the distinctive visual side effect that is unique to it among SARMs. Other SARMs such as MK 2866 or LGD 4033 have different selectivity profiles, half-lives, and side effect characteristics. The appropriate choice, if any, depends on individual goals and risk tolerance.

What is the difference between S4 and ostarine?

Both are SARMs, but they have different pharmacokinetic and side effect profiles. Andarine has a shorter half-life (approximately 4 hours) and is known for its distinctive visual side effects, while MK 2866 (ostarine) has a longer half-life and is generally considered milder with fewer distinctive side effects.

What is the difference between S4 and RAD 140?

Both are SARMs, but RAD 140 is generally considered more androgenic and is often referenced for strength and aggression, while andarine is referenced for lean muscle preservation and has the unique visual side effect profile. RAD 140 has not been studied in human clinical trials.

Is 25 mg of andarine a lot?

Andarine has no established human dosage. In non-medical contexts, 25 mg per day is commonly referenced as a conservative starting point, with reference ranges extending to 50–75 mg per day. Visual side effects are dose-dependent and may appear at moderate doses. S4 25 mg is labeled at 25 mg per tablet.

What strength is S4 25 mg?

S4 25 mg is labeled at 25 mg of andarine per tablet. It is supplied in a 100-tablet package, giving 2,500 mg of total labeled andarine content.

Is andarine approved for human use?

No. Andarine is not approved by the FDA for any human indication and is classified as an unapproved new drug when sold for human consumption. It is prohibited by WADA at all times.

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