GHK-CU 50 mg is a lyophilized copper peptide research product manufactured by Peptide Hubs and supplied as a 50 mg/vial powder in a 2 mL vial.
GHK-CU 50 mg contains the copper-binding tripeptide glycyl-L-histidyl-L-lysine complexed with copper(II), commonly known as Copper Tripeptide-1 or GHK-Cu. This naturally occurring peptide is found in human plasma, saliva, and urine, with concentrations that decline with age. It has been studied extensively in dermatological and tissue-remodeling research contexts.
In research settings, GHK-CU has been investigated for its role in collagen synthesis, angiogenesis, and anti-inflammatory responses. A 2008 review by Pickart described GHK-Cu as activating a "plethora of remodeling related processes," including chemoattraction of repair cells, anti-inflammatory actions, increased protein synthesis of collagen and elastin, and increased proliferation of fibroblasts and keratinocytes. These properties have generated interest in non-medical bodybuilding communities, where it is commonly referenced for skin quality, connective tissue support, and recovery applications. However, injectable GHK-CU is not FDA-approved, and its regulatory status remains unsettled.
Preclinical studies suggest GHK-CU may modulate gene expression related to tissue remodeling and stimulate fibroblast proliferation. Human clinical evidence for injectable use remains limited, though topical formulations have been more extensively studied for cosmetic applications. The FDA has removed injectable GHK-Cu from its Category 2 list and intends to consult the Pharmacy Compounding Advisory Committee regarding potential inclusion on the 503A bulks list.
GHK-CU 50 mg is supplied as a lyophilized (freeze-dried) powder in a 2 mL vial. Reconstitution with an appropriate solvent is required before use in research or non-medical contexts.
GHK-CU is a copper-binding tripeptide with a molecular weight of approximately 402.92 g/mol (free base) or 461.96 g/mol (acetate salt). Its amino acid sequence is glycyl-L-histidyl-L-lysine, complexed with a copper(II) ion.
GHK-CU belongs to a class of copper-binding peptides investigated for tissue-remodeling and regenerative properties. The peptide portion delivers copper to cells, where it serves as a cofactor for enzymes involved in collagen cross-linking and antioxidant defense. Unlike anabolic steroids or growth hormone secretagogues, GHK-CU does not act through androgen or growth hormone pathways.
Research has demonstrated that GHK-CU can stimulate collagen, elastin, and glycosaminoglycan synthesis in fibroblast cultures. It has also been shown to promote angiogenesis and modulate inflammatory responses in animal models. A 2026 PubMed review noted that GHK-Cu showed promise in wound healing and anti-inflammatory effects, but no clinical data support its use for musculoskeletal conditions.
In non-medical bodybuilding contexts, GHK-CU is commonly referenced for skin quality, connective tissue integrity, and recovery support, though such use lacks rigorous clinical validation for injectable administration. A 2026 dermatology ethics paper noted that injectable peptides marketed for anti-aging, including GHK-Cu, are not FDA-approved and that there is insufficient evidence to understand their benefit-risk profiles.
GHK-CU is distinguished by its ability to form a stable complex with copper(II). This copper-binding property is central to its proposed mechanisms, as the copper ion serves as a cofactor for lysyl oxidase and other enzymes involved in extracellular matrix remodeling.
Peptide Hubs offers several research peptides targeting different aspects of recovery and tissue health. Within this lineup, BPC 157 is commonly discussed alongside GHK-CU for its tissue-repair properties, though the two peptides operate through distinct mechanisms—BPC-157 primarily through angiogenic and cytoprotective pathways, and GHK-CU through copper-mediated collagen synthesis.
For research focused on soft-tissue recovery, TB 500 represents another peptide commonly referenced in this context, with a different amino acid sequence and mechanism of action. For research requiring a reconstitution solution, Bacteriostatic Water is the standard diluent for preparing lyophilized peptides like GHK-CU 50 mg.
Published laboratory reports for GHK-CU 50 mg are shown below with the test date, measured content, and batch number.
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Laboratory results apply to the specific tested sample represented in each published report and should not be interpreted as a measurement of every vial or production batch.
The information below is provided for educational reference only. Injectable GHK-CU is not an FDA-approved human drug. Its use for any non-medical purpose falls outside approved indications, and no established human dosing regimen exists for injectable administration.
Because injectable GHK-CU lacks FDA approval and published human dose-finding trials, there is no medically established dosage range. In non-medical bodybuilding and research communities, reference ranges are derived from community convention. Commonly referenced ranges are 100–300 mcg per day subcutaneously, with some protocols referencing up to 1–2 mg administered twice weekly for muscle-related research.
| Use Case | Common Reference Range | Injection Frequency |
|---|---|---|
| Conservative start (non-medical) | 100 mcg | Once daily |
| Standard protocol (non-medical) | 200 mcg | Once daily |
| Muscle/research focus (non-medical) | 1–2 mg | Twice weekly |
These ranges are community conventions, not evidence-based medical recommendations. No human dose-response relationship has been established for injectable GHK-CU, and individual response is unpredictable.
GHK-CU 50 mg is supplied as a lyophilized powder and requires reconstitution before use. In non-medical contexts, bacteriostatic water is commonly used as the solvent. A 50 mg vial reconstituted with 2 mL of solvent yields a concentration of 25 mg/mL, meaning a 1 mg dose would require drawing 0.04 mL (4 units on a U-100 insulin syringe).
Reconstituted peptide is typically stored refrigerated at 2–8°C and used within approximately 30 days. Unreconstituted powder is more stable and should be kept frozen for long-term storage.
In non-medical bodybuilding contexts, GHK-CU is sometimes combined with BPC 157 for recovery-focused protocols, as the two peptides are believed to address complementary aspects of tissue repair. Most protocols run 5 days on, 2 days off, in cycles of 4 to 12 weeks.
For those seeking to combine GHK-CU 50 mg with growth hormone support, Ipamorelin is sometimes referenced in community protocols, though this represents a combination of different mechanisms rather than a validated synergistic stack.
No human pharmacokinetic or dose-response data exists for injectable GHK-CU. All dosage information is derived from community convention and should not be interpreted as medical guidance.
GHK-CU is not FDA-approved for injectable human use. The FDA has evaluated GHK-Cu for inclusion on the 503A bulk drug substances list and intends to consult the Pharmacy Compounding Advisory Committee regarding its potential inclusion.
Injectable GHK-CU has not undergone the clinical trials required for FDA approval as a human drug. A 2026 dermatology ethics paper noted that injectable peptides marketed for anti-aging, including GHK-Cu, are not FDA-approved and that there is insufficient evidence to understand their benefit-risk profiles.
Unregulated sourcing introduces risks of contamination and mislabeling, and improper injection technique may cause serious complications. The FDA removed injectable GHK-Cu from Category 2 in early 2026, but it does not currently appear on the 503A bulks list.
Injectable GHK-CU is marketed as a research peptide, but it is not FDA-approved for any human indication. Non-medical use falls outside approved indications and should be approached with caution.
Human safety data for injectable GHK-CU is minimal. Potential concerns include skin irritation, redness, or sensitivity with topical use, variable absorption depending on formulation, lack of long-term safety data, and risk of infection or dosing errors with injections.
Copper overdose is a theoretical concern with excessive dosing, as copper is an essential trace mineral with a Tolerable Upper Intake Level of 10 mg per day for oral intake. Copper toxicity can lead to multi-organ failure, neurologic impairment, and even death. As a peptide administered parenterally, GHK-CU may pose immunogenicity risks.
Given the absence of human safety data for injectable use, any consideration of GHK-CU should involve consultation with a qualified healthcare professional. Individuals with copper metabolism disorders, liver disease, or known sensitivity to copper should exercise particular caution.
No established monitoring protocol exists for injectable GHK-CU. In research contexts, any adverse reactions should be documented and reported to appropriate authorities.
Store lyophilized powder at -20°C for up to 3 years, or at 4°C for up to 2 years. Protect from light and moisture. Once reconstituted, store refrigerated at 2–8°C and use within approximately 30 days. Keep out of reach of children.
GHK-CU 50 mg is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging with discreet handling.
The outer shipping package remains discreet, with privacy-focused handling. Products are supplied through the official Peptide Hubs distribution chain.
To verify your GHK-CU 50 mg product, use the security code on the vial label and cross-check it on the Peptide Hubs official site. Original packaging and manufacturer presentation help reinforce product legitimacy.
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Proper storage conditions help preserve peptide stability and integrity throughout shelf life.
Store lyophilized powder at -20°C for up to 3 years, or at 4°C for up to 2 years. Protect from light and moisture. The powder is stable at ambient temperature for a few days during shipping, which is why it can be shipped without refrigeration.
Once reconstituted, store refrigerated at 2–8°C and use within approximately 30 days. Avoid repeated freeze-thaw cycles.
Keep out of reach of children. Follow proper handling practices.
Answers to common questions about GHK-CU 50 mg, Copper Tripeptide-1, and research peptide handling.
GHK-CU 50 mg is a copper peptide studied in preclinical settings for its potential effects on collagen synthesis, tissue remodeling, and skin repair. In non-medical bodybuilding contexts, it is commonly referenced for skin quality and connective tissue support, though injectable use falls outside approved indications.
No established human dosing schedule exists for injectable GHK-CU. Community protocols commonly reference once-daily subcutaneous administration at 100–300 mcg, or 1–2 mg twice weekly for muscle-related research.
GHK-CU does not suppress endogenous testosterone production and does not require post-cycle therapy in the way anabolic steroids do. However, any non-medical peptide use should be approached with caution given the absence of human safety data for injectable administration.
Copper Tripeptide-1 (GHK-CU) is a naturally occurring peptide that binds copper and delivers it to cells. Research suggests it may stimulate collagen and elastin synthesis, promote angiogenesis, and modulate inflammatory responses in tissue-remodeling contexts.
No human data establishes a timeline for injectable GHK-CU effects. Preclinical research and topical cosmetic studies suggest effects on skin quality may appear over weeks to months, but translation to injectable use is speculative.
GHK-CU is the most extensively studied copper peptide, but there is no universally “best” copper peptide. Comparative human data for injectable administration is absent, and individual response to any peptide is unpredictable.
GHK-CU is a copper-binding tripeptide studied for collagen synthesis and skin remodeling, while BPC 157 is a larger peptide studied for angiogenesis and cytoprotection. They operate through different mechanisms and are not interchangeable.
GHK-CU is a copper tripeptide focused on collagen and skin-related pathways, while TB 500 is a thymosin beta-4 fragment studied for cell migration and tissue repair. They have different amino acid sequences and proposed mechanisms.
Without human dose-response data for injectable GHK-CU, it is impossible to characterize any amount as appropriate or excessive. Community protocols commonly reference 100–300 mcg per day for conservative use, with some protocols referencing up to 1–2 mg twice weekly for muscle-related research.
GHK-CU 50 mg is labeled at 50 mg of GHK-CU per vial. It is supplied as a lyophilized powder in a 2 mL vial.
Yes. The latest published laboratory report dated January 12, 2026 measured GHK-CU 50 mg at 61.51 mg, equivalent to 123.0% of its 50 mg label claim. The batch number is GAGHK12.
Store the lyophilized powder at -20°C for up to 3 years, or at 4°C for up to 2 years. Protect from light and moisture. Once reconstituted, refrigerate at 2–8°C and use within approximately 30 days.